
Noble Mount Flannel Pajama Set
Made from 100% cotton flannel, the Noble Mount flannel pajama set was made for cuddling up on chilly nights. The cuffed sleeves and bottoms add elegance, and shoppers love that the set is available in multiple colors. Plus, the adjustable drawstring makes them perfect for lounging. Don’t forget to take a look at our picks for the best men’s pajamas too.

PajamaMania Button-Down Pajama Set
With more than 4,300 five-star ratings, this wallet-friendly flannel pajama set from Amazon is ideal for fall and winter lounging. It’s made from 100% cotton to keep you warm, while the soft, brushed feel offers maximum comfort. Choose from dozens of prints, some of which even come with holiday packaging for easy gift-giving.

Lane Bryant Comfy Cotton Sleep Shorts
We know that not everyone lives where there are bitter winters, and sometimes winter may be hot and humid. That’s why these cotton sleep shorts from Lane Bryant are perfect. They’ll not only keep you cozy and comfortable while lounging around the house but they’re oh-so-cute. The elastic waistband and relaxed fit ensure freedom of movement and much-needed comfort for plus-size bodies, especially when you’re trying to sleep.

By Anthropologie Wide Leg Sleep Pants
Yes, women’s flannel pajamas come in more than just plaid prints. These stylish flannel sleep pants come in a beautiful, illustrative print with natural and supernatural motifs. They’re comfortable enough to wear around the house, but beautiful enough to wear out while running errands. The green colorway is perfect for spring too.

L.L.Bean Scotch Plaid Flannel Pajamas
For many people, plaid is synonymous with flannel pajamas, and this classic set from L.L.Bean is a good reason why. Made from the brand’s exclusive Portuguese cotton flannel, the button-front top and pull-on pants are expertly brushed for exceptional softness and warmth. They’re also yarn-dyed to stay vibrant no matter how often you wash them, though you’ll definitely want to wash them in the correct water temperature.
And customers adore them. “I love the weight and soft fabric of these pajamas,” says Carole B., one of the hundreds of five-star reviewers. “The colors are dark and rich. They fit perfectly.”

Serena & Lily Dalton Flannel Pajamas
Every item from Serena & Lily makes a design statement, and this cozy flannel pajama set whispers, “Relax. Stay in bed.” Crafted in Portugal from 100% woven cotton flannel, it’s eco-friendly and OEKO–TEX–certified, so you’ll rest easy knowing it’s free of harmful chemicals.
Piping along the collar and cuff adds a polished finish, and the button-down top features mother-of-pearl buttons. Heathered for a soft, lived-in look, these women’s flannel pajamas will feel like old favorites right out of the package—and will immediately become the best women’s pajamas you’ve ever owned.

Petite Plume Gingham Cotton Flannel Pajama Set
The timeless print is a wardrobe staple, and yes, that goes for sleepwear too. This gingham flannel pajama set comes in a crisp navy with white piping. It’s made from 100% cotton to keep warm and cozy at night and feel fresh in the morning. Complete the look with a pair of warm socks for the coziest winter nights.

Maurices Drawstring Pajama Joggers
Prefer flannel pajamas that don’t drag on the floor with every step? These drawstring pajama joggers are an excellent choice for anyone who wants to be comfortable at home but loves the functionality that comes with wearing a pair of joggers. The drawstring waist allows for easy customization to ensure all-day comfort. Pair these joggers with a complementary top for a great loungewear set.

Amazon Essentials Flannel Sleep Pant
The best flannel drawstring pants come in multiple prints, like this pair of flannel sleep pants from Amazon. We love that they come in prints for both everyday wear and the holidays. The adjustable drawstring puts comfort first while the 100% cotton material keeps legs warm yet breathable. With over 3,000 five-star ratings, Amazon shoppers give these pants high marks for comfort and price.
Kelly B., a verified Amazon reviewer, shares, “These are the perfect pajama bottoms. Very comfortable and fit as expected. I love that they have a drawstring around the waist. These are a must-have.”

Lanz of Salzburg Cotton Flannel Pajama Set
Lanz of Salzburg has been making traditional cotton flannel sleepwear for more than 60 years, and they’ve definitely perfected it. This classic set is everything one expects from a pair of flannel pajamas: It’s soft and comfortable with a notch-collar, button-down top and a drawstring elastic waist. Plus, it has pockets and comes in five cozy prints, including two plaids. If you’re looking for the perfect gift for your mom, the search is over.

Old Navy Matching Flannel Pajama Set
Old Navy never fails to deliver high-quality, comfortable basics and this plaid flannel set is exactly what you need for a chilly night in. Crafted with ultra-soft and breathable fabric, the snug material will keep anyone comfortably wrapped while binge-watching a Netflix show, or sipping on hot cocoa under a throw blanket. The pajamas come in four fall and winter-inspired colors that’ll certainly get you in the mood for the chillier seasons.

Silver Lilly Oh Deer Buffalo Flannel One-Piece Pajamas
“This is the absolute best one-piece on the market,” writes verified Amazon reviewer Kathy Mayall. “Mainly [because] the trap door in the bottom allows you to go to the restroom without having to take it off your shoulders. So comfortable, and no riding up or down or twisting.”
Hundreds of other five-star reviewers agree. Made of 100% cotton, this onesie has a flattering, slim-fit silhouette and even features side seam pockets. It’s perfect for snuggly winter mornings, whether you’re vacationing in a cozy cabin or staying put at home.

SelineLounge Monogrammed Flannel Pajamas
They may be called “Christmas” pajamas, but these flannel beauties are perfect for any time. Because you don’t want anyone “accidentally” walking off with yours, personalize them with a name, monogram or clever phrase.
Choose from a variety of plaids and styles (long sleeves, short sleeves, long pants or shorts), all of which are handmade and can be custom-sized. Buy them for the whole family, bridesmaids or whomever else you want to get matchy-matchy with.
With additional reporting by Lois Alter Mark.
Stop hunting for the best products and deals—get our expert scoop on secret sales and discounts, gift ideas for everyone and can’t-miss products. Sign up for the Stuff We Love newsletter.